Endocrine Abstracts

Introduction: Diabetes mellitus (DM) is one of the main causes of end-stage renal disease (ESRD). Renal transplantation is the most effective form or renal replacement.Methods: Retrospective, descriptive study of a sample of 108 diabetic patients admitted as candidates to renal transplant from January 1991 to December 2011, using the SPSS programme, version 20.0.Results: 11 women and 97 men were evaluated (medium age: 58±8.2 y...

Background: Data on sexual dysfunction (SD) in cirrhotic patients are limited. Our aim was to evaluate the sexual function of patients with end-stage liver disease and to compare it with the results after liver transplant (LT) and with that of a controlled group matched by age and gender.Methods: Changes in sexual functioning questionnaire were used to evaluate SD in cirrhotic patients awaiting LT and in the post-LT setting 1 year after transplant. Clini...

Introduction: Craniopharyngiomas are benign epitelial tumors located in the suprasellar region and they are associated to several comorbidities. Our aim is to describe hormonal deficiency and complications after surgery.Design: Descriptive study of patients that underwent surgery of craniopharyngioma. Data collected included hormonal levels, clinical data and mortality. Quantitative variables with normal distribution are shown as mean and standard deviat...

Introduction: The TNM staging system for well differentiated thyroid cancer (WDTC) considers tumours over 4 cm diameter limited to the thyroid or tumours with minimal extra-thyroid extension to be classified as pT3. This stage can be considered quite heterogeneous, as different clinical and pathologic characteristics seem to have distinct prognosis value.Aims: To determine prognostic factors amongst clinical, laboratorial, histologic and radiologic chara...

Introduction and objective: Prophylactic central lymph node dissection (CLND) in patients with suspected papillary thyroid cancer (PTC) without evident lymph node metastasis (LNM), remains debatable. We propose to evaluate whether BRAF V600E mutation presence, could help to identify patients at risk for LMN.Methods: Retrospective study of patients with diagnosis of PTC, who underwent total thyroidectomy during 2002 and 2013 (n: 256) in our hospi...

Objectives: SGLT2 inhibitors and GLP1 analogs are the treatment of choice after metformin in patients with type 2 diabetes (DM2) and overweight-obesity (OB). The aim of this study is to analyze the effectiveness and safety of these treatments alone or in combination.Methodology: This is a retrospective observational study in the usual clinical practice. We analyzed the effects of SGLT2 inhibitors and GLP1 analogs treatments in patients with DM2 and OB wh...

Aim: To assess ET1 levels in diabetic patients with and without microangiopathy, and compared with normal subjects, nondiabetic, without underlying vascular pathology.Introduction: The pathophysiology of diabetic microangiopathy is complex and many important aspects of it still are not fully understood. Endothelial dysfunction is of major importance in the pathogenesis of atherosclerosis and diabetic angiopathy. ET-1 is one of the most potent vasoconstri...

Introduction: Data on sexual dysfunction (SD) in cirrhotic patients are limited. Sexual function is a complex area of human behavior with great impact on quality-of-life (QOL). Despite its relevance, it is rarely evaluated in clinical practice in cirrhotic patients. Indeed, published studies are heterogeneous, differ in the way sexual function is assessed, and usually evaluate only one specific aspect of sexual life. Our aim was to evaluate in detail the sexual function of pat...

Introduction and objective: Neuroendocrine tumors (NETs) are relatively rare tumors. The majority are located in the gastrointestinal (GI) tract and bronchopulmonary system. The aim of this report is to study the characteristics of gastrointestinal NETs at diagnosis.Material and methods: Descriptive study about 18 patients diagnosed of gastrointestinal NETs during 1993–2011 in our hospital. Data regarding demographic, clinical, analytical, anatomopa...

Aim: Patients with malignant neuroendocrine tumors (mNETs) present frequently metastatic disease at diagnosis or during their follow-up. Hepatic transplant (HT) and radionuclide treatment have proved to be successful treatments. The aim of this report is to study the progression of the disease in patients with metastasic mNETs and HT.Patients and methods: Descriptive and retrospective study of patients diagnosed of metastasic mNETs and submitted to HT du...